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Abstract S. Pyogenes Final_submitted.pdf

abstract-s_pyogenes_final_submitted_2014_icaac_abstract.pdf
Preview of Abstract S. pyogenes final_submitted
🔗 Source: sciensano.be
📊 Size: 233 KB
👤 Author: Julia
⬇️ Downloads: 71

Summary

Group A Streptococcus (GAS) cause diseases from throat to severe invasive infections, with a global resurgence of severe invasive infections by serotype Emm protein 1 (M1) GAS in the last two decades. Researchers studied invasive M1 GAS from 1994-2013 using Whole Genome Mapping, finding nearly identical maps with minor genomic changes driven by prophages, and dividing them into 5 distinct sub-clusters. Genomic differences were detected, including insertions and deletions, with one insertion encoding an intact prophage φNIH1 predicted to harbour the SpeC exotoxin. The Belgian M1 GAS were most similar to a Japanese sepsis isolate, M1 476, showing remarkable genomic stability over 20 years.

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Group A Streptococcus (GAS) cause diseases from throat to severe invasive infections, with a global resurgence of severe invasive infections by serotype Emm...

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  • File Format: PDF
  • File Size: 233 KB
  • Pages: 2
  • Language: EN
  • Author: Julia
  • Total Downloads: 71
  • Last Updated: 1 month ago

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