Complement-Mediated Hemolysis In CAD And The MOA Of Sutimlimab, The First Approved Treatment For CAD (PDF).pdf

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Preview of Complement-Mediated Hemolysis in CAD and the MOA of Sutimlimab, the First Approved Treatment for CAD (PDF)
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📊 Size: 650 KB
📄 Pages: 1 page
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Summary

Complement-Mediated Hemolysis in CAD and the MOA of Sutimlimab: IgM (cold agglutinins) bind C1 complex, activating the classical complement pathway, leading to red blood cell destruction through extravascular and intravascular hemolysis. Sutimlimab binds C1s, inhibiting the classical complement pathway.

Description

Complement-Mediated Hemolysis in CAD and the MOA of Sutimlimab: IgM (cold agglutinins) bind C1 complex, activating the classical complement pathway, leading to...

Technical Information

  • File Format: PDF
  • File Size: 650 KB
  • Pages: 1
  • Language: EN
  • Total Downloads: 117
  • Last Updated: 1 month ago

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