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KYNASTON Howard - Utilisation of the STEAP protein family.pdf
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🔗 Source: orca.cardiff.ac.uk
📊 Size: 1.16 MB
👤 Author: Stephanie E. A. Burnell, Samantha Spencer-Harty, Suzie Howarth, Owen Bodger, Howard Kynaston, Claire
⬇️ Downloads: 49

Summary

Prostate cancer is the second most common cancer diagnosed in men worldwide, but few patients are affected by clinically significant disease within their lifetime. The means to discriminate between patients with indolent disease and those who progress to aggressive prostate cancer is currently unavailable, resulting in over-treatment of patients. Researchers aimed to determine biomarkers of prostate cancer that can be used in the clinic to aid diagnosis and prognosis. They found that the protein expression levels of STEAP2 correlated significantly with Gleason score, and STEAP4 was a significant predictor of relapse, indicating that STEAP2 could be a potential prognostic candidate for use in combination with current prostate cancer detection methods, and the presence of STEAP4 could be an indicator of possible relapse.

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Description

Prostate cancer is the second most common cancer diagnosed in men worldwide, but few patients are affected by clinically significant disease within their...

Technical Information

  • File Format: PDF
  • File Size: 1.16 MB
  • Pages: 11
  • Language: EN
  • Author: Stephanie E. A. Burnell, Samantha Spencer-Harty, Suzie Howarth, Owen Bodger, Howard Kynaston, Claire
  • Total Downloads: 49
  • Last Updated: 1 week ago

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