Evolution Of “design” Principles In Biochemical Networks.pdf

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Preview of Evolution of “design” principles in biochemical networks
🔗 Source: postpythagorean.com
📊 Size: 280 KB
👤 Author: lwilkers
⬇️ Downloads: 263

Summary

The authors argue that despite the challenges of characterizing biological systems, evolution leads to recurring, dynamic organizational principles in these systems, which can be identified and analyzed through simulation. They propose that biological systems, like engineered systems, can be understood in terms of "design principles" such as modularity, and that simulation can help to identify these principles and analyze their dynamic properties. The authors use the example of the galactose utilization pathway in yeast to illustrate their point, and suggest that the efficiency and conservation of certain cellular pathways across species can be understood in terms of logical organizational principles. They also draw parallels between the evolution of biological and engineered systems, highlighting the role of optimization, trade-offs, and the emergence of recurring organizational motifs.

Description

The authors argue that despite the challenges of characterizing biological systems, evolution leads to recurring, dynamic organizational principles in these...

Technical Information

  • File Format: PDF
  • File Size: 280 KB
  • Pages: 42
  • Language: EN
  • Author: lwilkers
  • Total Downloads: 263
  • Last Updated: 5 days ago

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