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Revised-ms_JPRI_79818_v1.pdf
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📊 Size: 289 KB
👤 Author: [email protected]
⬇️ Downloads: 52

Summary

Atrial Fibrillation is common among Americans, causing irregular heart rhythm and increasing the risk of stroke due to clot formation. Anticoagulants, such as warfarin, have been used to decrease stroke risk by 50%, but have drawbacks like slow onset, bleeding risk, and frequent monitoring requirements. Newer oral anticoagulants, including Pradaxa (dabigatran), Xarelto (rivaroxaban), and Eliquis (apixaban), have been approved by the FDA, offering better alternatives to warfarin with similar "blood thinner" effects, but also causing bleeding. These direct oral anticoagulants target thrombin and factor Xa, providing efficacy advantages over indirect inhibitors like heparin.

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Description

Atrial Fibrillation is common among Americans, causing irregular heart rhythm and increasing the risk of stroke due to clot formation.

Technical Information

  • File Format: PDF
  • File Size: 289 KB
  • Pages: 9
  • Language: EN
  • Author: [email protected]
  • Total Downloads: 52
  • Last Updated: 1 week ago

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