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Mehdi_FImputeV2.1.pdf
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📊 Size: 331 KB
👤 Author: msargol
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Summary

Researchers evaluated the accuracy and efficiency of FImpute v2.2, Beagle, Impute2, and Pedimpute for imputing genotypes in a large Holstein dataset. FImpute v2.2 outperformed other programs in terms of accuracy and computational efficiency, especially when combining family and population imputation. The study used a dataset of 105,182 genotyped animals and considered chromosomes 1 to 8. Validation was done on 20,000 animals with 50k genotypes, which were masked to 3k, 6k, and 8k panels. FImpute v2.2 achieved high concordance rates (98.01-99.49%) and required significantly less CPU time compared to Beagle and Impute2. Pedimpute also performed well but had higher missing call rates. The results suggest that FImpute v2.2 is a suitable choice for large-scale genotype imputation in livestock populations.

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Description

Researchers evaluated the accuracy and efficiency of FImpute v2.2, Beagle, Impute2, and Pedimpute for imputing genotypes in a large Holstein dataset.

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  • File Format: PDF
  • File Size: 331 KB
  • Pages: 10
  • Language: EN
  • Author: msargol
  • Total Downloads: 60
  • Last Updated: 1 month ago

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