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Summary

Two 12-week randomized, double-blind, placebo-controlled trials were conducted to determine the efficacy and tolerability of on-demand dapoxetine in patients with premature ejaculation. 2614 men were randomized to receive placebo, 30 mg dapoxetine, or 60 mg dapoxetine. Dapoxetine significantly prolonged intravaginal ejaculatory latency time (IELT) compared to placebo, with mean IELT increasing from 0.9-0.92 minutes at baseline to 1.75, 2.78, and 3.32 minutes for placebo, 30 mg dapoxetine, and 60 mg dapoxetine, respectively. Common adverse events included nausea, diarrhea, headache, and dizziness. The study concluded that on-demand dapoxetine is an effective and generally well-tolerated treatment for men with moderate-to-severe premature ejaculation.

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Two 12-week randomized, double-blind, placebo-controlled trials were conducted to determine the efficacy and tolerability of on-demand dapoxetine in patients...

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  • File Format: PDF
  • File Size: 322 KB
  • Pages: 9
  • Language: EN
  • Total Downloads: 36
  • Last Updated: 1 month ago

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