Reviewer Report.pdf

Reviewer Michelle Hall critiques the manuscript "Reductions in co-contraction following neuromuscular re-education in people with knee osteoarthritis" for clarity, methodology, and conclusions. Key points include:
- Ensure the study is referred to as an uncontrolled study throughout.
- Clarify how current treatments affect muscle co-contraction and central pain processing.
- Provide clear definitions and explanations of AT therapy and its effects on pain and function.
- Specify sample size estimation and participant experience with AT training.
- Use the "Consensus on Exercise Reporting Template (CERT)" for greater detail on the training.
- Include equations for co-contraction calculations and references.
- Report p-values and statistical differences throughout results.
- Revise discussions to reflect exploratory data and basis for future work, avoiding overstatements.
- Address potential factors for null observations, such as sample size.
- Ensure consistent reporting of results and clarify improvements in pain.
- Define points on plots in figures and indicate statistical significance.
- Assess whether methods are appropriate and well-described, and if necessary controls are included.
- Evaluate if conclusions are adequately supported by data.
- The reviewer declares no competing interests and agrees to the open peer review policy.