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"Simulation Of Polyethylene Glycol And Calcium-mediated Membrane Fusion".pdf

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Preview of "Simulation of polyethylene glycol and calcium-mediated membrane fusion"
🔗 Source: pure.rug.nl
📊 Size: 1.28 MB
📄 Pages: 8 pages
⬇️ Downloads: 76

Summary

Researchers simulated polyethylene glycol (PEG) and calcium-mediated membrane fusion using a coarse-grained molecular dynamics approach. The study found that PEG chains reduce the inter-lamellar distance and increase the concentration of divalent cations, which stabilizes a focal contact between negatively charged membranes. This contact acts as a nucleation site for further adhesion and subsequent stalk formation, explaining the synergistic effect of Ca2+ and PEG on membrane fusion.

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Description

Researchers simulated polyethylene glycol (PEG) and calcium-mediated membrane fusion using a coarse-grained molecular dynamics approach.

Technical Information

  • File Format: PDF
  • File Size: 1.28 MB
  • Pages: 8
  • Language: EN
  • Total Downloads: 76
  • Last Updated: 1 month ago

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"Simulation guide"Simulation tutorialpolyethylene guidepolyethylene tutorialglycol guideglycol tutorialcalcium-mediated guidecalcium-mediated tutorialmembrane guidemembrane tutorialfusion" guidefusion" tutorial

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