OI Impact & Funds 2020.pdf

- Osteogenesis Imperfecta (OI) Facts:
- 500,000 people worldwide have OI, with varying prevalence in different countries.
- OI is one of 7,000 rare diseases, collectively the 4th largest disease classification.
- Some people with OI break bones up to 200 times in their lifetime.
- 8,500 babies are born annually with OI, and there are no medications specifically developed for it.

- Care4BrittleBones Foundation in 2020:
- Organized 23 workshops and events.
- Raised 112,882 EUR for OI research.
- Spent/allocated 134,068 EUR towards research, information sharing, and collaboration.
- Overhead: 9.4%, Fundraising Cost: 11.3%.

- 2020 Impact and Challenges:
- Started the year with momentum but faced unique challenges due to global health and economic crises.
- Successfully ran a Proposal Round for research projects and secured valuable grants.
- Continued involvement in the "Key for OI" project and other initiatives.
- Expressed gratitude to sponsors, clinicians, researchers, and people with OI for their support.

- OI Description:
- A genetic bone condition caused by insufficient collagen production, leading to bone fragility.
- Symptoms include frequent fractures, physical deformities, pain, and psychosocial challenges.
- Five main types of OI with varying severity; children are most affected.
- Key symptoms to improve: fractures, pain, anxiety, and isolation.

- Care4BrittleBones' Goal:
- To enable scientific research that improves the quality of life of people with OI and ultimately find a cure.