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1-s2.0-S135380202030 8257-main.pdf

1-s2.0-S1353802020308257-main.pdf

🔗 Source: is.muni.cz

📊 Size: 2.48 MB

👤 Author: Alzbeta Sejnoha Minsterova

⬇️ Downloads: 178

Summary

Diffusion kurtosis imaging was used to evaluate white matter and basal ganglia microstructure in Parkinson's disease (PD) subtypes. The study found significant increases in diffusion kurtosis metrics in the substantia nigra, premotor, and motor cortices in PD patients with normal cognition compared to healthy participants. Combined diffusion markers in gray matter reached 81% accuracy in differentiating between the two groups. Significant white matter microstructural changes and kurtosis decreases in the cortex were present in cognitively impaired PD patients. Diffusion parameters from white and gray matter differentiated between PD phenotypes with 78% accuracy, supporting the utility of diffusion kurtosis imaging for PD diagnostics.

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Description

Diffusion kurtosis imaging was used to evaluate white matter and basal ganglia microstructure in Parkinson's disease (PD) subtypes.

Technical Information

File Format: PDF
File Size: 2.48 MB
Pages: 7
Language: EN
Author: Alzbeta Sejnoha Minsterova
Total Downloads: 178
Last Updated: 1 week ago

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