10.1056@NEJMoa201543 2.pdf

10.1056NEJMoa2015432.pdf
Preview of 10.1056@NEJMoa201543 2
🔗 Source: orvosikannabisz.info
📊 Size: 1.09 MB
👤 Author: Maximilian Ackermann, Stijn E. Verleden, Mark Kuehnel, Axel Haverich, Tobias Welte, Florian Laenger,
⬇️ Downloads: 69

Summary

Researchers examined lungs from 7 Covid-19 patients, 7 influenza patients, and 10 uninfected controls, finding diffuse alveolar damage and perivascular T-cell infiltration in both Covid-19 and influenza patients. However, Covid-19 patients had distinctive vascular features, including severe endothelial injury, intracellular virus, and disrupted cell membranes, with widespread thrombosis and microangiopathy. Alveolar capillary microthrombi were 9 times more prevalent in Covid-19 patients than in influenza patients, and new vessel growth was 2.7 times higher in Covid-19 patients. These findings suggest that vascular angiogenesis distinguishes Covid-19 from equally severe influenza virus infection.

Description

Researchers examined lungs from 7 Covid-19 patients, 7 influenza patients, and 10 uninfected controls, finding diffuse alveolar damage and perivascular T-cell...

Technical Information

  • File Format: PDF
  • File Size: 1.09 MB
  • Pages: 9
  • Language: EN
  • Author: Maximilian Ackermann, Stijn E. Verleden, Mark Kuehnel, Axel Haverich, Tobias Welte, Florian Laenger,
  • Total Downloads: 69
  • Last Updated: 1 week ago

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