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Changing the Course of Autism" by Bryan Jepson, MD, provides a scientific overview of autism, reviewing its history and evolution from a psychiatric disease model to current biomedical understandings and treatment approaches. The book explores the complexities of autistic behaviors, including gastrointestinal, immunological, and neurological issues, and discusses emerging science on epigenetic phenomena and detoxification systems. Jepson, a physician who changed his career path after his son's autism diagnosis, presents a roadmap for healthcare professionals and parents to understand the condition. The text covers topics such as vaccination protocols, nutritional and pharmacologic approaches, and physiological treatments, and includes extensive reference lists. The book aims to revolutionize thought on autism and garner attention from the medical community, media, and government officials, with the goal of changing the course of autism.