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Biomarker-based Stability In Limbic-predominant Amnestic Mild Cognitive Impairment.pdf

Tondo-2021-Biomarker-based stability in limbic.pdf
Preview of Biomarker-based stability in limbic-predominant amnestic mild cognitive impairment
🔗 Source: adni.loni.usc.edu
📊 Size: 1022 KB
📄 Pages: 11 pages
⬇️ Downloads: 128

Summary

Researchers studied 142 patients with amnestic mild cognitive impairment (aMCI) over 4-19 years, using cerebrospinal fluid (CSF) measures and [18F]fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging to predict prognosis. They found that aMCI patients with a limbic-predominant FDG-PET pattern showed clinical stability, with only 7% converting to dementia, whereas those with an AD-like FDG-PET pattern had a high rate of dementia progression (86%). The FDG-PET patterns predicted stability or conversion with high accuracy, sensitivity, and specificity, making them a useful tool for identifying aMCI patients who are unlikely to progress to Alzheimer's disease.

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Description

Researchers studied 142 patients with amnestic mild cognitive impairment (aMCI) over 4-19 years, using cerebrospinal fluid (CSF) measures and...

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  • File Format: PDF
  • File Size: 1022 KB
  • Pages: 11
  • Language: EN
  • Total Downloads: 128
  • Last Updated: 4 days ago

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