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COVID-19 Vaccine Efficacy Report.pdf

COVAX_Transmission_Workshop_REPORT_FINAL_MPJGAyT.pdf
Preview of COVID-19 Vaccine Efficacy Report
🔗 Source: media.tghn.org
📊 Size: 404 KB
👤 Author: Julia Granerod Whitehouse
⬇️ Downloads: 44

Summary

A workshop on "Pre- and Post-Licensure Assessments of COVID-19 Vaccine Efficacy/Effectiveness Against Infection & Transmission" was held on December 17th, 2020. Key points included:
• The design approach to COVID-19 Phase 3 efficacy trials will need to shift as vaccines receive EUA/licensure and become increasingly available.
• Evidence of high efficacy from several vaccines suggests the modest neutralization titres demonstrated in phase 1/2 clinical studies may be sufficient for short-term protection regardless of the vaccine platform.
• Transmission risk is highest on the day of symptom onset and the duration of infectiousness is about one week in most patients.
• A vaccine which gives 90% efficacy against disease can still result in high population mortality in the absence of efficacy against transmission or non-pharmaceutical interventions (NPIs).
• Even if vaccines offer high efficacy against infection/transmission, high coverage in the general population will be necessary to stop transmission.
• Household studies, longitudinal prospective community-based cohort studies and outbreak investigations can yield important insights on impact of vaccines on transmission.

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Description

A workshop on "Pre- and Post-Licensure Assessments of COVID-19 Vaccine Efficacy/Effectiveness Against Infection & Transmission" was held on December 17th,...

Technical Information

  • File Format: PDF
  • File Size: 404 KB
  • Pages: 14
  • Language: EN
  • Author: Julia Granerod Whitehouse
  • Total Downloads: 44
  • Last Updated: 2 weeks ago

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This PDF document about COVID-19 Vaccine Efficacy Report provides comprehensive information and guidance. Whether you're a beginner or advanced user, this resource offers valuable insights into COVID-19 Vaccine Efficacy Report.

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