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Elevated Transaminase As Coma Predictor In Anorexia Nervosa: A Case Report Review.pdf

13256_2010_1264_ReviewerReport_V1_R1.pdf
Preview of Elevated Transaminase as Coma Predictor in Anorexia Nervosa: A Case Report Review
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Summary

- Title: Elevated transaminase can be a predictor of coma in anorexia nervosa patients.
- Type of Case Report: The report presents findings that provide new insights into the possible pathogenesis of a disease or adverse effect.

Review Findings:
- Coherence and Authenticity: The case is reported coherently, authentically, ethically, and with patient anonymity protected. However, it lacks persuasiveness and does not significantly impact clinical practice.
- Explanatory Value: The report has explanatory value but no diagnostic value.

Comments for Authors:
1. Language errors need correction by a native speaker.
2. Correct "Grasgow coma scale" to "Glasgow coma scale."
3. Clarify the meaning of “regular BS with clear consciousness.”
4. Focus on clinically relevant lab results, omitting unnecessary details.
5. Incorporate recent case reports about hepatic dysfunction in anorexia nervosa into the discussion for comparative analysis:
- Dowman et al., 2009: Discusses recurrent acute hepatic dysfunction in severe anorexia nervosa.
- Welsh et al., 2010: Examines iatrogenic hyperammonemia after anorexia.
6. Address the lack of psychiatric referral despite the patient's life-threatening condition due to a major psychiatric disorder, emphasizing the importance of treating the underlying psychiatric condition.

Quality and Competing Interests:
- The manuscript requires language corrections before publication.
- The reviewer declares no competing interests.

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Description

The reviewer evaluates a case report titled "Elevated transaminase can be a predictor of coma in anorexia nervosa patients," noting it provides new insights into disease pathogenesis. The report is coherent, authentic, ethical, and worth publishing despite lacking persuasiveness and diagnostic value. It lacks some information before publication but protects patient anonymity. Language errors are present, including the misspelling of "Glasgow coma scale."

Technical Information

  • File Format: PDF
  • File Size: 3 KB
  • Pages: 2
  • Language: EN
  • Total Downloads: 166
  • Last Updated: 2 months ago

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