Harms In Trials.pdf

Ioannidis-2009-Adverse events in ra.pdf
Preview of Harms in Trials
🔗 Source: olympias.lib.uoi.gr
📊 Size: 60 KB
📄 Pages: 3 pages
⬇️ Downloads: 125

Summary

Randomized trials often fail to report or adequately report adverse events, with many trials giving no information on harms, severity being undefined, and half reporting no information on patient withdrawal due to harms. Reporting of adverse events is often restricted, distorted, or silenced, with some trials only reporting common or severe harms, or statistically significant differences, which can be misleading. Poor reporting may reflect neglected collection of adverse events, lack of reporting, or distorted reporting, and may be influenced by conflicts of interest and marketing needs. Accurate reporting of harms is essential for evidence-based practice, and randomized trials should prioritize the evaluation of harms, rather than just effectiveness.

Description

Randomized trials often fail to report or adequately report adverse events, with many trials giving no information on harms, severity being undefined, and half...

Technical Information

  • File Format: PDF
  • File Size: 60 KB
  • Pages: 3
  • Language: EN
  • Total Downloads: 125
  • Last Updated: 1 week ago

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