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020496s021lbl.pdf
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🔗 Source: accessdata.fda.gov
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👤 Author: fda
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Summary

AMARYL (glimepiride tablets) is an oral blood-glucose-lowering drug of the sulfonylurea class, available in 1, 2, and 4 mg strengths. Glimepiride stimulates insulin release from pancreatic beta cells and increases peripheral tissue sensitivity to insulin. It is effective as initial therapy and in combination with metformin, with a synergistic effect in improving glucose tolerance. The drug has a mild glucose-lowering effect, with peak levels reached 2-3 hours after administration, and is completely absorbed from the GI tract. Glimepiride is completely metabolized by oxidative biotransformation, with major metabolites M1 and M2, and is excreted primarily in the urine and feces.

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Description

AMARYL (glimepiride tablets) is an oral blood-glucose-lowering drug of the sulfonylurea class, available in 1, 2, and 4 mg strengths.

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  • File Format: PDF
  • File Size: 266 KB
  • Pages: 14
  • Language: EN
  • Author: fda
  • Total Downloads: 235
  • Last Updated: 17 hours ago

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