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MicroRNA Signature.pdf

jcm-11-00612.pdf
Preview of MicroRNA Signature
🔗 Source: ncbi.nlm.nih.gov
📊 Size: 729 KB
👤 Author: Sofiane Bendifallah, Stéphane Suisse, Anne Puchar, Léa Delbos, Mathieu Poilblanc, Philippe Descamps,
⬇️ Downloads: 131

Summary

Researchers identified a saliva-based diagnostic miRNA signature for endometriosis, a condition affecting 2-10% of women worldwide. The study involved 200 women with chronic pelvic pain, with 76.5% diagnosed with endometriosis. Small RNA sequencing yielded 4642 million raw sequencing reads, mapping to 2561 known miRNAs. A Random Forest algorithm generated a signature of 109 miRNAs, with 96.7% sensitivity, 100% specificity, and 98.3% AUC. This non-invasive diagnostic tool could improve early diagnosis and reduce the economic burden of endometriosis on healthcare systems.

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Description

Salivary microRNA signature is used for diagnosing endometriosis.
Research published in Journal of Clinical Medicine in 2022.
Authors include Bendifallah, Suisse, and Puchar.

Technical Information

  • File Format: PDF
  • File Size: 729 KB
  • Pages: 12
  • Language: EN
  • Author: Sofiane Bendifallah, Stéphane Suisse, Anne Puchar, Léa Delbos, Mathieu Poilblanc, Philippe Descamps,
  • Total Downloads: 131
  • Last Updated: 2 weeks ago

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