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Neurodegeneration In MS.pdf

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Preview of Neurodegeneration in MS
🔗 Source: research.vumc.nl
📊 Size: 423 KB
👤 Author: Axel Petzold {et al.}
⬇️ Downloads: 154

Summary

Patients with multiple sclerosis (MS) rank loss of visual function second only to loss of mobility in terms of impact on quality of life. Optical coherence tomography (OCT) is a rapidly evolving technology that can quantify loss of retinal axons with high accuracy, potentially representing an objective outcome measure for treatment trials. Several reviews discuss the use of OCT and other imaging techniques, such as MRI, to assess neurodegeneration in MS and related disorders, including neuromyelitis optica. Biomarker research is also highlighted, with a focus on oxidative damage, iron, and neurofilament proteins as potential markers of neurodegeneration. Standardization of biomarker research is emphasized, and the need for readily accessible measures of disease progression is noted.

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Description

Patients with multiple sclerosis (MS) rank loss of visual function second only to loss of mobility in terms of impact on quality of life.

Technical Information

  • File Format: PDF
  • File Size: 423 KB
  • Pages: 2
  • Language: EN
  • Author: Axel Petzold {et al.}
  • Total Downloads: 154
  • Last Updated: 4 days ago

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