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A retrospective analysis of 100 patients with intermediate-advanced hepatocellular carcinoma (HCC) treated with donafinib or lenvatinib from January 2021 to June 2022 showed that donafinib had a higher disease control rate (70% vs 50%, P < 0.05) and longer survival time (P < 0.05) compared to lenvatinib. The objective remission rate was higher in the donafinib group (32% vs 20%, P > 0.05), but not statistically significant. Both treatments significantly reduced serum levels of alpha-fetoprotein (AFP), Golgi glycoprotein 73 (GP-73), and glypican-3 (GPC3) (P < 0.05). Adverse reaction rates were similar between the two groups (P > 0.05). The study suggests that donafinib may be a more effective treatment option for intermediate-advanced HCC patients.

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A retrospective analysis of 100 patients with intermediate-advanced hepatocellular carcinoma (HCC) treated with donafinib or lenvatinib from January 2021 to...

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  • File Format: PDF
  • File Size: 379 KB
  • Pages: 7
  • Language: EN
  • Total Downloads: 56
  • Last Updated: 2 months ago

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