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Signalling Pathways
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29 documents available in our comprehensive collection of Signalling Pathways resources. Find practical guides, tutorials, and documentation to enhance your knowledge.
Download (4MB) (1752-0509-2-36.pdf)
4.49 MBEN 15 pages
Researchers created a logic-based diagram of signaling pathways central to macrophage activation, integrating four key pathways: toll-like receptor,
EGR1プロモーター経路 (EGR1-pathway-man.pdf)
420 KBEN 10 pages
GenTarget offers ready-to-use lentivirus for EGR1-Promoter Pathway Reporter, which monitors EGR1-promoter signaling pathway with luminescent, fluorescent, or...
Télécharger le fichier (ptpmcrender.pdf)
1.44 MBEN 16 pages
Loss of auditory sensory hair cells is the most common cause of hearing loss, and this review addresses the signaling pathways involved in their programmed and
Ellagic Acid Ameliorates Enteritis (latest.pdf)
1.97 MBEN 28 pages
Dietary ellagic acid alleviates subclinical necrotizing enteritis in broilers by regulating inflammation signaling pathways, relieving oxidative stress, and
PDF (Stepanova_et_al_2019_J.Neurochem.pdf)
902 KBEN 15 pages
Reactive oxygen species (ROS) are by-products of mitochondrial metabolism involved in cellular signaling pathways and tissue injury
Tuberculosis Research (jci-130-134622.pdf)
4.55 MBEN 11 pages
Tuberculosis (TB) patients have DNA hypermethylation of IL-2/STAT5, TNF/NF-κB, and IFN-γ signaling pathways, associated with decreased immune responsiveness,
Phospho-C-Raf (RX2905_TDS.pdf)
107 KBEN 1 page
Phospho-C-Raf (Ser-471) is involved in the Ras-Raf-MAP kinase signaling pathway, controlling cell proliferation and differentiation, with phosphorylation at...
Download (1566Kb) (WRAP-Extensive-signal-integration-phytohormone-protein-network-Bassel-2020 1.pdf)
1.53 MBEN 30 pages
Researchers generated a systems-level map of the Arabidopsis phytohormone signaling network, consisting of over 2,000 binary protein-protein interactions.
Green Version (2311.full.pdf)
1.63 MBEN 15 pages
Nuclear lamina defects cause ATM-dependent NF-kB activation and link accelerated aging to a systemic inflammatory response.
Cancer Stem Cells (cancer-stem-cells-unraveling-the-secrets-of-tumor-heterogeneity.pdf)
231 KBEN 1 page
Cancer stem cells are a subpopulation of cells within tumors that exhibit stem cell-like properties, contributing to tumor initiation, growth, and resistance...
Involvement of Phospholipase C in the (09-SM53-Q2-TAPIA-et-al.pdf)
315 KBEN 9 pages
Norepinephrine (NE) mediates cardiomyocyte hypertrophy through the G protein coupled α1-adrenoceptor (α1-AR) and the activation of phosphoinositide-specific...
Dicer & Muscle Atrophy (s41598-021-98545-0.pdf)
1.65 MBEN 11 pages
Dicer-mediated miRNA processing is not involved in controlling muscle mass during muscle atrophy, as Dicer knockout in adult skeletal muscle did not affect...
Download PDF 848 downloads (2659.pdf)
1.3 MBEN 10 pages
Hepatocellular carcinoma (HCC) is a common and fatal malignancy with a complex, multi-step process and poor prognosis.
Download (904kB) (SD_Transcriptomic_analysis.pdf)
883 KBEN 18 pages
Weaning of beef calves induces a stress response, altering behavior, hormonal mediators, and immune function.
Green Version (s41598-017-06510-7.pdf)
1.77 MBEN 10 pages
Itraconazole, an antifungal drug, has anti-cancer effects against epithelial ovarian cancer (EOC) by inhibiting endothelial cell proliferation and...
PDF (d41586-023-02935-5.pdf)
298 KBEN 2 pages
Valtcheva et al. injected viral tracers into oxytocin neurons of maternal mice to label brain areas sending auditory information to these neurons.
Apigenin Functions (excli2020-2579.pdf)
813 KBEN 8 pages
Apigenin has various bioactive functions, including antibacterial, antiviral, antiproliferative, anti-inflammatory, antioxidant, antiangiogenic, and anticancer...
Green Version (82881696.pdf)
1.71 MBEN 16 pages
The ongoing climate change is characterized by increased temperatures and altered precipitation patterns, with more frequent and intense droughts affecting...
Cancer Inflammation (Cancer-related inflammation_Nature.pdf)
967 KBEN 9 pages
Links between cancer and inflammation were first made in the nineteenth century, with observations that tumors often arose at sites of chronic inflammation and...
Finding New Medications based on the Knowledge of a Biological Target. (finding-new-medications-based-on-the-knowledge-of-a-biological-target.pdf)
99 KBEN 1 page
Drug design is the process of finding new medications based on the knowledge of a biological target, typically a protein or nucleic acid, involved in a...
VS-6766 Inhibitor (Pachter-Verastem-AACR-NCI-EORTC-meeting-Oct-2021-FINAL.pdf)
961 KBEN 7 pages
VS-6766 is a dual RAF/MEK inhibitor that inhibits both MEK and RAF kinase activities, providing an advantage over MEK inhibitors by not inducing MEK...
Chemical Research (220318-Technical.pdf)
152 KBEN 5 pages
Bisphenol A replacement chemicals BPF and BPS induce protumorigenic changes in human mammary gland organoids.
See Source (DELIVERY-of-antibody-mimics-into-mammalian-cells.pdf)
1.13 MBEN 9 pages
Antibody mimics have significant scientific and therapeutic utility for disrupting protein-protein interactions inside cells, but their delivery to the cell...
Download pdf (9bda0044afc40c5998d24a1d6c189096.pdf)
111 KBEN 3 pages
2019 APS Outstanding Contribution Awards recognize outstanding papers, reviewers, and guest editors in Acta Pharmacologica Sinica.
OTULIN's Role in Skin Homeostasis and Keratinocyte Regulation (41467_2021_25944_MOESM2_ESM.pdf)
3.97 MBEN 20 pages
File licensed under CC BY 4.0. Attribution required, with credit to original authors and source.
Stem Cell Symposium (2019symposiumposters.pdf)
59 KBEN 4 pages
1. Spatially restricted stromal Wnt signaling suppresses prostatic epithelial stem cell proliferation
2. Genome reorganization during human cardiogenesis
3.
Cigarette Smoke Exposure Animal Models of COPD: Procedural Variations and Apparatus (pdf-143005-71104)
627 KBEN 8 pages
This review article explores various animal models induced by cigarette smoke exposure to study chronic obstructive pulmonary disease (COPD), highlighting procedural variations and the apparatus used in research. It provides an overview of current methods and tools in...
Protein Structures and Functions: Insights from Antibodies to Enzymes (12900_2008_220_MOESM7_ESM.pdf)
84 KBEN 17 pages
The document describes various proteins and their structures or functions. It includes the Diels-Alder catalytic antibody with transition state analogue (extracellular), Trypanosoma cruzi trypanothione reductase in its oxidized form (cytoplasm), glutathione S-transferase...
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