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Lysosomales

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3 documents available in our comprehensive collection of Lysosomales resources. Find practical guides, tutorials, and documentation to enhance your knowledge.

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Download PDF (Intracranial_Hypertension_in_Cystinosis_Is_a_Challenge__Experience_in_a_Children_s_Hospital._-_PubMed_-_NCBI.pdf)

100 KBEN 1 page
Intracranial hypertension is a challenge in cystinosis, a rare systemic lysosomal disease.
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Preview of Macrophage Differentiation Model
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Macrophage Differentiation Model (12950_2015_60_MOESM1_ESM.pdf)

126 KBNora LieggiEN 1 page
HBPMCs differentiate into macrophages in 8 days when stimulated with 100 ng/ml M-CSF, transitioning from a classical monocyte phenotype to immature macrophages...
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Preview of Unified Mechanism of Proteolysis and Autocatalytic Activation in the 20S Proteasome
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Unified Mechanism of Proteolysis and Autocatalytic Activation in the 20S Proteasome (ncomms10900.pdf)

1.22 MBEva M HuberEN 10 pages
This article reveals a unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome, identifying Lys33 and Thr1 as key components of a catalytic triad, with Thr1 substitution inactivating the enzyme.
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