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Eastman Pharmaceutical Excipients.pdf

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Preview of Eastman Pharmaceutical Excipients
🔗 Source: eastman.com
📊 Size: 104 KB
📄 Pages: 2 pages
⬇️ Downloads: 58

Summary

Cellulose Esters for Sustained Release
- CA-398-10 NF/EP, CA-320S NF/EP, CAB-171-15 NF
- Semipermeable, strong, flexible film formers for coatings
- Coating properties modifiable through blending CAs or CA with CAB
- Directly compressible, matrix for sustained release tablets
- CAB more hydrophobic than CA
- Applications: osmotic drug delivery, extended-release tablets, taste masking, sustained release binders
- Formulation tips: solvent required, additives for varied film properties, blend CA with CAB for sustained release

Enteric Coating Polymer - C-A-P NF
- pH-sensitive, hydrolyzes at pH 6 or higher
- Solvent-based, stable in sealed, cool, dry containers
- Two physical forms: powder, pellet; compressible
- Multiple plasticizers suitable
- Advantage: coats small tablets, water-sensitive actives
- Applications: enteric coating, delayed release binders
- Formulation tips: solvent systems, plasticizers for flexibility, ammonia neutralization for aqueous systems, low usage levels (0.5%)

Disclaimer
- Information provided in good faith, but no representations or warranties made
- User responsible for determining suitability, environmental protection, and health/safety
- No patent infringement guarantees
- Safety Data Sheets available, observe safety precautions
- Trademarks acknowledged
- Contact information: Eastman Corporate Headquarters, P.O. Box 431, Kingsport, TN 37662-5280 U.S.A.

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Description

Cellulose esters are used for sustained release in pharmaceuticals. Key attributes include semipermeable coatings, excellent film formation, and strong, flexible properties. They can be modified through blending for various applications.

Technical Information

  • File Format: PDF
  • File Size: 104 KB
  • Pages: 2
  • Language: EN
  • Total Downloads: 58
  • Last Updated: 2 weeks ago

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