Additional File 1: In Pdf Format Includes Supplementary Figures 1–6.(PDF 591 KB).pdf

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Preview of Additional file 1: In Pdf format includes Supplementary Figures 1–6.(PDF 591 KB)
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📊 Size: 591 KB
👤 Author: hzare
⬇️ Downloads: 170

Summary

Figures S1-S5 show various analyses of miRNA targeting and gene regulation. Figure S1 plots the number of miRNAs targeting 3'UTR versus the absolute number of miRNA sites per gene, with overlap between quartile groups. Figure S2 presents GO analysis of 1st and 4th quartile groups, showing enriched Molecular Function and Cellular Component terms. Figure S3 compares miRNA targeting of transcription factors and tissue-specific genes, with brain-specific genes enriched in the 4th quartile. Figure S4 analyzes promoter GC content and nucleosome favoring di-nucleotides, suggesting higher transcription noise in the 4th quartile. Figure S5 replicates analyses using miRanda predicted sites, showing similar results to TargetScan.

Description

Figures S1-S5 show various analyses of miRNA targeting and gene regulation.

Technical Information

  • File Format: PDF
  • File Size: 591 KB
  • Pages: 6
  • Language: EN
  • Author: hzare
  • Total Downloads: 170
  • Last Updated: 3 weeks ago

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