Antibody Mimetics.pdf

2017_Antibody_Mimetics_QCM_D_MB_Affimers.pdf
Preview of Antibody Mimetics
🔗 Source: eprints.whiterose.ac.uk
📊 Size: 1.01 MB
👤 Author: Koutsoumpeli, Eleni, Tiede, Christian, Murray, James, Tang, Anna, Bon, Robin, Tomlinson, Darren and
⬇️ Downloads: 68

Summary

Researchers explored the potential of Affimers, antibody mimetics, as bio-receptors for detecting small organic compounds, specifically methylene blue, using quartz crystal microbalance with dissipation monitoring (QCM-D). They found that Affimers offer high affinity and specificity, comparable to antibodies, with reduced batch-to-batch variability and high stability. The study demonstrated the selectivity of Affimers in complex matrices and their potential in immunoassays for detecting small-sized, non-immunogenic compounds, addressing challenges in conventional immunoassays.

Description

Researchers explored the potential of Affimers, antibody mimetics, as bio-receptors for detecting small organic compounds, specifically methylene blue, using...

Technical Information

  • File Format: PDF
  • File Size: 1.01 MB
  • Pages: 11
  • Language: EN
  • Author: Koutsoumpeli, Eleni, Tiede, Christian, Murray, James, Tang, Anna, Bon, Robin, Tomlinson, Darren and
  • Total Downloads: 68
  • Last Updated: 1 month ago

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