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Anticancer Thiosemicarbazones.pdf

ARS_2019_Heffeter.pdf
Preview of Anticancer Thiosemicarbazones
🔗 Source: real.mtak.hu
📊 Size: 825 KB
👤 Author: Dr. Petra Heffeter, Dr. Veronika F. S. Pape, Dr. Eva A Enyedy, Dr. Bernhard K. Keppler, Prof. Gergel
⬇️ Downloads: 87

Summary

Thiosemicarbazones have been developed for various diseases, including cancer, and have shown promise as anticancer agents, particularly the α-N-heterocyclic thiosemicarbazones, with Triapine being the most extensively tested in clinical phase I/II trials, although its efficacy against solid tumors is limited due to rapid metabolism, short plasma half-life, and potential drug resistance.

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Description

Thiosemicarbazones have been developed for various diseases, including cancer, and have shown promise as anticancer agents, particularly the α-N-heterocyclic...

Technical Information

  • File Format: PDF
  • File Size: 825 KB
  • Pages: 63
  • Language: EN
  • Author: Dr. Petra Heffeter, Dr. Veronika F. S. Pape, Dr. Eva A Enyedy, Dr. Bernhard K. Keppler, Prof. Gergel
  • Total Downloads: 87
  • Last Updated: 1 month ago

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