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Cardioplegia Report.pdf

13019_2014_155_ReviewerReport_V2_R1.pdf
Preview of Cardioplegia Report
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Summary

Thatte and colleagues explored the hypothesis that warm cardioplegic arrest with SOMAH solution offers superior myocardial protection compared to hypothermic arrest. They used a large animal model, arresting and storing pig hearts at either 21°C or 4°C, then measuring hemodynamic indices, high energy phosphates, and cardiac enzymes. Results showed that warm arrest hearts had higher levels of high energy phosphates and better functional recovery after storage, with higher coronary flow and no need for inotropic support. The reviewer suggests revisions, including clarifying terminology and addressing statistical issues, but believes the manuscript merits publication, finding the methods appropriate and results consistent with other observations.

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Thatte and colleagues explored the hypothesis that warm cardioplegic arrest with SOMAH solution offers superior myocardial protection compared to hypothermic...

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  • File Format: PDF
  • File Size: 7 KB
  • Pages: 4
  • Language: EN
  • Total Downloads: 119
  • Last Updated: 3 weeks ago

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