Development. 113 (4):1335-1344..pdf

Levi_Devel_12_91_141_0.pdf
Preview of Development. 113 (4):1335-1344.
🔗 Source: weizmann.ac.il
📊 Size: 9.69 MB
📄 Pages: 12 pages
⬇️ Downloads: 116

Summary

EP-cadherin is a Ca2+-dependent adhesion molecule in Xenopus laevis embryos, sharing homology with mouse E- and P-cadherins. It is expressed in oocytes, eggs, and blastomeres, increasing in non-neural ectodermal cells, somites, and notochord during gastrulation. Expression declines in the nervous system during neurulation but persists in endodermal cells and decreases in migratory cells. In later development, EP-cadherin is prominent in epidermis and skeletal muscle, disappearing from muscle tissue after metamorphosis. It is often coexpressed with E-cadherin in epidermal cells but has a different subcellular distribution, suggesting distinct roles in tissue differentiation and morphogenesis.

Description

EP-cadherin is a Ca2+-dependent adhesion molecule in Xenopus laevis embryos, sharing homology with mouse E- and P-cadherins.

Technical Information

  • File Format: PDF
  • File Size: 9.69 MB
  • Pages: 12
  • Language: EN
  • Total Downloads: 116
  • Last Updated: 12 hours ago

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