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🔗 Source: sciensano.be
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📄 Pages: 11 pages
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Researchers propose a unified classification system for human respiratory syncytial virus (HRSV) genotypes, addressing inconsistent conclusions and nomenclature issues. They analyzed over 12,000 bp of complete HRSV genomes, dividing them into subgroups HRSV-A and HRSV-B, and extracted regions corresponding to the glycoprotein G and second hypervariable region (HVR2). Phylogenetic trees and patristic distances were used to determine genotype criteria, defining a genotype as a clade with ≥70% bootstrap support and maximum patristic distance of ≤0.018 substitutions per site for HRSV-A or ≤0.026 for HRSV-B. This approach identified 23 genotypes within HRSV-A and 6 within HRSV-B, providing a robust method for HRSV genotype classification.

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Researchers propose a unified classification system for human respiratory syncytial virus (HRSV) genotypes, addressing inconsistent conclusions and...

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  • File Format: PDF
  • File Size: 654 KB
  • Pages: 11
  • Language: EN
  • Total Downloads: 84
  • Last Updated: 4 days ago

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