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🔗 Source: discovery.ucl.ac.uk
📊 Size: 6.54 MB
👤 Author: Paride Antinucci
⬇️ Downloads: 102

Summary

Researchers identified a class of orientation-tuned amacrine cells with elongated dendritic arbors, characterized by the expression of the cell-adhesion molecule Teneurin-3 (Tenm3), which are essential for generating orientation selectivity in retinal ganglion cells. The study found that Tenm3+ amacrine cells provide GABAergic inhibition to retinal ganglion cells, and that orientation tuning is also present in some bipolar cell presynaptic terminals. The results define a neural circuit underlying orientation selectivity in the vertebrate retina and characterize the cellular and molecular requirements for its assembly.

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Researchers identified a class of orientation-tuned amacrine cells with elongated dendritic arbors, characterized by the expression of the cell-adhesion...

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  • File Format: PDF
  • File Size: 6.54 MB
  • Pages: 15
  • Language: EN
  • Author: Paride Antinucci
  • Total Downloads: 102
  • Last Updated: 1 week ago

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