EGFR T790 Wild-Type Clones.pdf

nihms688121.pdf
Preview of EGFR T790 Wild-Type Clones
🔗 Source: ncbi.nlm.nih.gov
📊 Size: 1 MB
📄 Pages: 22 pages
⬇️ Downloads: 88

Summary

Rociletinib, a third-generation EGFR inhibitor, is active in lung cancers with T790M mutation, but resistance mechanisms emerge, including T790 wild-type clones, EGFR amplification, and small cell lung cancer transformation, highlighting the role of tumor heterogeneity in resistance to targeted therapies.

Description

Rociletinib, a third-generation EGFR inhibitor, is active in lung cancers with T790M mutation, but resistance mechanisms emerge, including T790 wild-type...

Technical Information

  • File Format: PDF
  • File Size: 1 MB
  • Pages: 22
  • Language: EN
  • Total Downloads: 88
  • Last Updated: 3 weeks ago

Document Overview

This PDF document about EGFR T790 Wild-Type Clones provides comprehensive information and guidance. Whether you're a beginner or advanced user, this resource offers valuable insights into EGFR T790 Wild-Type Clones.

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