Ferroptosis In Cancer.pdf

Ronbun_2022_12.pdf
Preview of Ferroptosis in Cancer
🔗 Source: jsbmg.jp
📊 Size: 181 KB
👤 Author: Takamasa ISHII
⬇️ Downloads: 195

Summary

Ferroptosis of tumour neutrophils causes immune suppression in cancer, according to a study by Rina Kim et al. published in Nature. The study found that ferroptosis, a type of iron-dependent cell death, induces immune suppression by promoting the production of immunosuppressive factors such as PGE2 and AA-PEox in tumour-associated neutrophils. The researchers used mouse models and human samples to demonstrate that ferroptosis is a key mechanism underlying the immune suppressive activity of tumour-associated neutrophils, and that inhibiting ferroptosis can enhance anti-tumour immunity.

Description

Ferroptosis of tumour neutrophils causes immune suppression in cancer, according to a study by Rina Kim et al. published in Nature.

Technical Information

  • File Format: PDF
  • File Size: 181 KB
  • Pages: 2
  • Language: EN
  • Author: Takamasa ISHII
  • Total Downloads: 195
  • Last Updated: 1 week ago

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