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Final Report.pdf

rr09_508.pdf
Preview of final report
🔗 Source: ntp.niehs.nih.gov
📊 Size: 5.09 MB
📄 Pages: 223 pages
⬇️ Downloads: 121

Summary

The National Toxicology Program (NTP) conducted a perinatal and chronic extended-dose-range study of Bisphenol A (BPA) in rats, known as the CLARITY-BPA Core Study. The study aimed to bridge guideline-compliant research with hypothesis-based research investigations on BPA toxicity. The core study was a chronic, extended-dose response design that evaluated the toxicologic potential of BPA following perinatal only or chronic exposure in rats. The study was funded by an interagency agreement between the FDA and NIEHS, and its conduct and progress were monitored by several committees. The study's results are based on a guideline-compliant chronic study conducted at the National Center for Toxicological Research (NCTR) according to FDA Good Laboratory Practice (GLP) regulations. The interpretation of biological and toxicological responses is based only on the results of the core GLP study, without integration with other data or extrapolation to other species, including humans.

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Description

The National Toxicology Program (NTP) conducted a perinatal and chronic extended-dose-range study of Bisphenol A (BPA) in rats, known as the CLARITY-BPA Core...

Technical Information

  • File Format: PDF
  • File Size: 5.09 MB
  • Pages: 223
  • Language: EN
  • Total Downloads: 121
  • Last Updated: 2 hours ago

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