Glyphosate Toxicological Profile: Health Risks And Environmental Impact.pdf

Disclaimer: This document does not imply endorsement by the Agency for Toxic Substances and Disease Registry (ATSDR) or the U.S. Department of Health and Human Services.

Foreword:
This ATSDR toxicological profile assesses glyphosate, a commonly used herbicide, based on peer-reviewed literature and other relevant sources. It provides a succinct characterization of its toxicological and adverse health effects, focusing on public health relevance.

Legislative Background:
Developed under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, this profile is part of a series aimed at supporting site-specific response actions and establishing an inventory of literature on toxic substances.

Version History:
- August 2020: Final toxicological profile released.
- April 2019: Draft for public comment toxicological profile released.

Key Points:

1. Exposure Assessment: Evaluates levels of significant human exposure to glyphosate, considering acute, intermediate, and chronic durations.

2. Health Effects Summary: Identifies and reviews key literature on glyphosate's toxicological properties, including its potential health effects.

3. Adequacy of Information: Determines the availability of data sufficient to assess health effects and identify risk levels for different exposure scenarios.

4. Identified Needs: Highlights areas where additional toxicological testing is needed to better understand the types and levels of exposure that may pose significant health risks.

Target Audiences: The profile is intended for health professionals, private sector organizations, local and federal governments, and the general public. It reflects ATSDR’s assessment, with peer review from CDC scientists and an external nongovernmental panel.