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H3K27ac Enrichment.pdf

13073_2021_970_MOESM2_ESM.pdf
Preview of H3K27ac Enrichment
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📊 Size: 35.78 MB
📄 Pages: 18 pages
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Summary

H3K27ac enrichment is observed at regions flanking TSS of housekeeping genes in all cell lines. Recurrent enhancers are defined as those occurring in at least 3 GC cell lines. Predicted super-enhancers associated with MYC, KLF5, and EGFR are recurrent in multiple GC cell lines. Tumour-present and tumour-gained enhancers are identified, with 52,457 and 23,273 enhancers, respectively. CapSTARR-seq signals are compared between replicates in OCUM1 and SNU16 cell lines, showing high correlation.

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H3K27ac enrichment is observed at regions flanking TSS of housekeeping genes in all cell lines.

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  • File Format: PDF
  • File Size: 35.78 MB
  • Pages: 18
  • Language: EN
  • Total Downloads: 110
  • Last Updated: 1 month ago

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