Https://www.biorxiv. Org/content/10.1101/ 2021.06.20.448993v1. Full.pdf

2021.06.20.448993v1.full.pdf
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Summary

Selectively expressing SARS-CoV-2 Spike protein S1 subunit in cardiomyocytes induces cardiac hypertrophy in mice, suggesting a novel ACE2-independent pathological role of SARS-CoV-2 Spike protein that may harm cardiomyocytes by triggering their innate immune responses through interaction with Toll-like receptor 4 (TLR4).

Description

Selectively expressing SARS-CoV-2 Spike protein S1 subunit in cardiomyocytes induces cardiac hypertrophy in mice, suggesting a novel ACE2-independent...

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  • File Format: PDF
  • File Size: 4 MB
  • Pages: 23
  • Language: EN
  • Total Downloads: 33
  • Last Updated: 1 month ago

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