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Impact Of Acquisition Time-window On Clinical Whole-body PET Parametric Imaging.pdf

karakatsanis_mic2014_acquisitiontimewindow_impact_on_wb_parametricpetimaging.pdf
Preview of Impact of acquisition time-window on clinical whole-body PET parametric imaging
🔗 Source: rahmimlab.files.wordpress.com
📊 Size: 1.5 MB
👤 Author: Bo Yu
⬇️ Downloads: 71

Summary

The impact of the acquisition time-window on whole-body PET parametric imaging was assessed, with a focus on FDG tracers. A sliding acquisition time-window of 35 minutes was shifted along an extended scan period of 0-90 minutes post-injection, using real patient kinetic data and realistic 4D simulations. The results showed that both standard and generalized Patlak methods resulted in enhanced tumor-to-background contrast and contrast-to-noise ratios with minimal bias at an early acquisition time window (10-45 minutes post-injection), with the generalized method exhibiting superior performance. The choice of the optimal time-window was found to be critical, and the generalized Patlak method, which accounts for tracer uptake reversibility, was proposed for more quantitative estimation of Ki parametric images.

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Description

The impact of the acquisition time-window on whole-body PET parametric imaging was assessed, with a focus on FDG tracers.

Technical Information

  • File Format: PDF
  • File Size: 1.5 MB
  • Pages: 8
  • Language: EN
  • Author: Bo Yu
  • Total Downloads: 71
  • Last Updated: 2 weeks ago

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