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Journal.pone.0287191 .pdf

journal.pone.0287191.pdf
Preview of journal.pone.0287191 .pdf
🔗 Source: eprints.whiterose.ac.uk
📊 Size: 2.19 MB
👤 Author: Oliver J. Hills, Zuzanna Poskrobko, Andrew J. Scott, James Smith, Helen F. Chappell
⬇️ Downloads: 132

Summary

A DFT study investigated the gallium ion-binding capacity of mature Pseudomonas aeruginosa biofilm extracellular polysaccharide, finding that gallium cannot substitute for calcium ions in the EPS scaffold, suggesting gallium may utilize a novel ferric uptake system to enter siderophore-deficient cells, and supporting its potential as a non-antibiotic therapeutic strategy for treating cystic fibrosis patients with mucoid P. aeruginosa biofilm lung infections.

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Description

A DFT study investigated the gallium ion-binding capacity of mature Pseudomonas aeruginosa biofilm extracellular polysaccharide, finding that gallium cannot...

Technical Information

  • File Format: PDF
  • File Size: 2.19 MB
  • Pages: 21
  • Language: EN
  • Author: Oliver J. Hills, Zuzanna Poskrobko, Andrew J. Scott, James Smith, Helen F. Chappell
  • Total Downloads: 132
  • Last Updated: 5 days ago

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