Marine Actinobacterium-Deri Ved Melanin: Antibacterial Activity And Isolation.pdf

This study investigates the isolation of melanin-producing marine actinobacteria from sediment samples and assesses their antibacterial activity. The researchers collected sediment samples from Parangipettai, Tamilnadu, and isolated actinobacteria using Kuster's Agar Medium. After identifying morphologically distinct colonies, pure cultures were obtained.

The focus is on Streptomyces species due to its large genus within Actinobacteria. Melanin production was confirmed through visual assessment of pigment color on specific media. The antibacterial potential of the extracted melanin was evaluated using the disc diffusion method and minimum inhibitory concentration (MIC) determination against a standard antibiotic, tetracycline.

Key findings include:
- Successful isolation and identification of marine actinobacteria, particularly Streptomyces species.
- Production of melanin by isolated strains, with varying colors indicating potential diversity in chemical composition.
- The melanin pigment exhibits potent antibacterial activity, surpassing the effect of tetracycline in some cases.

The study highlights the promise of microbial-mediated melanin production for scalable, cost-effective melanin synthesis and its potential bioactive properties, meriting further characterization.