Optical Resolution Of 1, Synthesis Of 3 And General Procedure For The Asymmetric Ring-opening Reaction Of Epoxide, And Fig. S1–S.pdf

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Preview of Optical resolution of 1, synthesis of 3 and general procedure for the asymmetric ring-opening reaction of epoxide, and Fig. S1–S
🔗 Source: rsc.org
📊 Size: 407 KB
👤 Author: tanaka
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Summary

Researchers synthesized a novel chiral porous metal-organic framework, (R)-3, and used it as a catalyst for the asymmetric ring-opening reaction of epoxide with amine. The reaction yielded (1S, 2S)-(+)-2-phenylaminocyclohexanol with 51% ee and 51% yield. The chiral framework was prepared by slowly diffusing N,N-dimethylaniline into a mixture solution of MeOH and water containing Cu(NO3)2 and (R)-(+)-1. The optical purity of the products was determined by HPLC analysis using a Chiralpak AD-H column.

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Researchers synthesized a novel chiral porous metal-organic framework, (R)-3, and used it as a catalyst for the asymmetric ring-opening reaction of epoxide...

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  • File Format: PDF
  • File Size: 407 KB
  • Pages: 4
  • Language: EN
  • Author: tanaka
  • Total Downloads: 59
  • Last Updated: 1 month ago

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