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Investigadores de São Paulo identificaron un posible mecanismo que ayuda al protozoario Trypanosoma cruzi a invadir células huésped. El parásito libera vesículas con proteínas y lípidos que facilitan su introducción en otras células. Estas vesículas, de 20 a 80 nanómetros de diámetro, contienen glicoproteínas, incluyendo la transialidasa, que activan proteínas en la membrana de células de defensa, estimulando la producción de moléculas que aumentan la respuesta inflamatoria y facilitan la invasión del parásito. El mal de Chagas, causado por el T. cruzi, afecta a alrededor de 10 millones de personas en América del Sur y se está convirtiendo en un problema de salud pública en Estados Unidos.

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Investigadores de São Paulo identificaron un posible mecanismo que ayuda al protozoario Trypanosoma cruzi a invadir células huésped.

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  • File Format: PDF
  • File Size: 6.55 MB
  • Pages: 4
  • Language: ES
  • Total Downloads: 127
  • Last Updated: 1 week ago

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