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sachdev_et_al_2022.pdf
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🔗 Source: lbk.fe.uni-lj.si
📊 Size: 3.06 MB
👤 Author: Shaurya Sachdev
⬇️ Downloads: 66

Summary

Gene therapy is revolutionizing medicine by providing treatments for devastating diseases, with several approved therapies for cancers, inheritable diseases, and infectious diseases. Gene electrotransfer (GET) is a non-viral technique that uses pulsed electric fields to overcome barriers to gene therapy, including interstitial, cell membrane, cytoplasmic, and nuclear envelope barriers. This review discusses the current understanding of GET from a biophysical perspective, critically evaluating the mechanisms by which electric fields aid in overcoming these barriers and identifying gaps in knowledge that hinder optimization of GET in vivo.

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Gene therapy is revolutionizing medicine by providing treatments for devastating diseases, with several approved therapies for cancers, inheritable diseases,...

Technical Information

  • File Format: PDF
  • File Size: 3.06 MB
  • Pages: 26
  • Language: EN
  • Author: Shaurya Sachdev
  • Total Downloads: 66
  • Last Updated: 19 hours ago

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