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vascular-endothelial-growth-factor-gene-polymorphisms-and-psoriasis-susceptibility-a-metaanalysis.pdf
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🔗 Source: geneticsmr.org
📊 Size: 497 KB
📄 Pages: 10 pages
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This meta-analysis examined the association between vascular endothelial growth factor (VEGF) gene polymorphisms and psoriasis susceptibility. Seven studies involving 1956 subjects were included, and the results showed no association between psoriasis and the VEGF +405 C allele in all subjects. However, stratification by ethnicity indicated a significant association between the VEGF +405 C allele and psoriasis in Asians, and between the VEGF -460 C allele and psoriasis in Europeans. Additionally, the -1154 A/G polymorphism was associated with psoriasis in Europeans, but the -2578 A/C polymorphism showed no association in all subjects or in Europeans or Asians. The study suggests that the VEGF +405 C/G polymorphism confers susceptibility to psoriasis in Asians, and the -460 C/T and -1154 A/G polymorphisms confer susceptibility to psoriasis in Europeans.

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This meta-analysis examined the association between vascular endothelial growth factor (VEGF) gene polymorphisms and psoriasis susceptibility.

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  • File Format: PDF
  • File Size: 497 KB
  • Pages: 10
  • Language: EN
  • Total Downloads: 62
  • Last Updated: 3 hours ago

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