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microrna-21-and-the-role-of-anti-apoptosis-in-human-cancers.pdf
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🔗 Source: pharmacophorejournal.com
📊 Size: 308 KB
📄 Pages: 4 pages
⬇️ Downloads: 68

Summary

MicroRNA-21 (miR-21) is an oncogene that plays a significant role in evading apoptosis, a hallmark of cancer. It is upregulated in many human cancers, including breast, hepatocellular, nasopharyngeal, and lung cancers. MiR-21 targets genes involved in anti-apoptosis, such as Bcl-2, PTEN, and PDCD4, leading to the inhibition of apoptosis and contributing to tumorigenesis. The dysregulation of miR-21 and its target genes is a valuable therapeutic target for the development of human cancer treatment.

Description

MicroRNA-21 (miR-21) is an oncogene that plays a significant role in evading apoptosis, a hallmark of cancer.

Technical Information

  • File Format: PDF
  • File Size: 308 KB
  • Pages: 4
  • Language: EN
  • Total Downloads: 68
  • Last Updated: 12 hours ago

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