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🔗 Source: link.springer.com
📊 Size: 7.02 MB
👤 Author: Peiye Song
⬇️ Downloads: 49

Summary

Estrogen receptor β (ERβ) inhibits breast cancer cell migration and invasion through CLDN6-mediated autophagy. ERβ upregulates CLDN6 expression, which induces autophagy by regulating beclin1. CLDN6 and beclin1 are positively correlated in breast cancer tissues, and ERβ/CLDN6/beclin1 expression is associated with good clinical outcome. The study suggests that ERβ may be a potential target for novel therapeutic avenues in breast cancer.

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Description

Estrogen receptor β (ERβ) inhibits breast cancer cell migration and invasion through CLDN6-mediated autophagy.

Technical Information

  • File Format: PDF
  • File Size: 7.02 MB
  • Pages: 18
  • Language: EN
  • Author: Peiye Song
  • Total Downloads: 49
  • Last Updated: 1 month ago

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