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Reviewer Report - Mathew Thayer.pdf

12885_2009_2029_ReviewerReport_V2_R1.pdf
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Summary

This manuscript reports on studies of epigenetic markers and aneuploidy levels in patients with hematological malignancies from diagnosis to full remission after allogeneic stem cell transplantation. The study found that aberrant asynchronous replication, observed in lymphocytes of cancer patients, is erased following transplantation, while increased aneuploidy levels persist. The results suggest that epigenetic aberrations can be reversed by stem cell transplantation, but aneuploidy remains unchanged.

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Description

This manuscript reports on studies of epigenetic markers and aneuploidy levels in patients with hematological malignancies from diagnosis to full remission...

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  • File Format: PDF
  • File Size: 4 KB
  • Pages: 2
  • Language: EN
  • Total Downloads: 51
  • Last Updated: 3 weeks ago

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