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Trans-splicing In Cells.pdf

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📊 Size: 5.27 MB
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Summary

Researchers identified 24,498 non-co-linear (NCL) events in human cells, with 20-35% arising from both trans-spliced RNAs (tsRNAs) and circular RNAs (circRNAs), indicating extensive alternative trans-splicing and cis-backsplicing. TsRNAs and circRNAs exhibit different expression patterns, including correlation with co-linear counterparts, expression breadth/abundance, transcript stability, and subcellular localization preference, suggesting distinct regulatory roles.

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Researchers identified 24,498 non-co-linear (NCL) events in human cells, with 20-35% arising from both trans-spliced RNAs (tsRNAs) and circular RNAs...

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  • File Format: PDF
  • File Size: 5.27 MB
  • Pages: 21
  • Language: EN
  • Total Downloads: 177
  • Last Updated: 7 days ago

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