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YONDELIS-pi.pdf
Preview of Full Prescribing Information
🔗 Source: janssenlabels.com
📊 Size: 660 KB
📄 Pages: 21 pages
⬇️ Downloads: 45

Summary

YONDELIS (trabectedin) is indicated for treating unresectable or metastatic liposarcoma or leiomyosarcoma in patients who received a prior anthracycline-containing regimen. The recommended dose is 1.5 mg/m2 as a 24-hour intravenous infusion every 3 weeks, with premedication of dexamethasone 20 mg intravenously 30 minutes prior to each dose. Dose modifications are recommended for adverse reactions, including neutropenia, thrombocytopenia, and hepatotoxicity. Contraindications include known hypersensitivity to trabectedin, and warnings include neutropenic sepsis, rhabdomyolysis, hepatotoxicity, cardiomyopathy, and capillary leak syndrome. Common adverse reactions include nausea, fatigue, vomiting, and diarrhea. YONDELIS can cause fetal harm, and effective contraception is recommended.

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Description

YONDELIS (trabectedin) is indicated for treating unresectable or metastatic liposarcoma or leiomyosarcoma in patients who received a prior...

Technical Information

  • File Format: PDF
  • File Size: 660 KB
  • Pages: 21
  • Language: EN
  • Total Downloads: 45
  • Last Updated: 2 months ago

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