L-column2 C8.pdf

L-column2 C8 is a next-generation high-performance silica-based octyl column with low adsorption, reduced analysis time, and high durability. Its advanced end-capping method minimizes residual silanol groups, allowing for sharp peaks and suitability for various compounds, including acids, bases, and chelating compounds.

Key features:
- Low adsorption: Suitable for analyzing compounds prone to adsorption, such as promethazine and clemastine.
- Reduced analysis time: Shorter retention times for hydrophobic analytes, conserving solvent and reducing analysis time.
- High durability: Chemically stable and reliable due to the advanced end-capping method.
- Improved separation: Sometimes offers better separation than C18 columns due to different elution behavior.

Specifications:
- Average particle size: 3 μm, 5 μm
- Average pore size: 120 Å
- Range of pH: 2–7.5
- USP category: L7

Applications:
- Suitable for reducing analysis time of hydrophobic compounds and conserving solvent.
- Improved separation of certain compounds, such as antidepressants, compared to C18 columns.